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<SDOBI lang="en"><B000><eptags><B001EP>ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESILTLVFIROMKCYALTRBGCZEEHU..SK....................................</B001EP><B003EP>*</B003EP><B005EP>J</B005EP><B007EP>DIM360 Ver 2.15 (14 Jul 2008) -  2999001/0</B007EP></eptags></B000><B100><B110>1511713</B110><B120><B121>CORRECTED EUROPEAN PATENT SPECIFICATION</B121></B120><B130>B8</B130><B132EP>B1</B132EP><B140><date>20120208</date></B140><B150><B151>W1</B151><B153>73</B153><B155><B1551>de</B1551><B1552>Bibliographie</B1552><B1551>en</B1551><B1552>Bibliography</B1552><B1551>fr</B1551><B1552>Bibliographie</B1552></B155></B150><B190>EP</B190></B100><B200><B210>03757173.4</B210><B220><date>20030606</date></B220><B240><B241><date>20041214</date></B241><B242><date>20070618</date></B242></B240><B250>en</B250><B251EP>en</B251EP><B260>en</B260></B200><B300><B310>386930 P</B310><B320><date>20020606</date></B320><B330><ctry>US</ctry></B330></B300><B400><B405><date>20120208</date><bnum>201206</bnum></B405><B430><date>20050309</date><bnum>200510</bnum></B430><B450><date>20110817</date><bnum>201133</bnum></B450><B452EP><date>20110131</date></B452EP><B480><date>20120208</date><bnum>201206</bnum></B480></B400><B500><B510EP><classification-ipcr sequence="1"><text>C07C 327/26        20060101AFI20101122BHEP        </text></classification-ipcr><classification-ipcr sequence="2"><text>C07C 327/36        20060101ALI20101122BHEP        </text></classification-ipcr><classification-ipcr sequence="3"><text>C07C  69/76        20060101ALI20101122BHEP        </text></classification-ipcr><classification-ipcr sequence="4"><text>A61K  31/216       20060101ALI20101122BHEP        </text></classification-ipcr><classification-ipcr sequence="5"><text>A61K  31/265       20060101ALI20101122BHEP        </text></classification-ipcr></B510EP><B540><B541>de</B541><B542>VERBINDUNGEN, DIE DEN DURCH DNA-SCHÄDIGUNG INDUZIERTEN G2-CHECKPOINT DES ZELLZYKLUS STILLLEGEN UND/ODER DIE ANTIKREBSWIRKUNG VON DNA-SCHÄDIGENDEN BEHANDLUNGEN ERHÖHEN</B542><B541>en</B541><B542>COMPOUNDS THAT ABROGATE DNA-DAMAGE-INDUCED CELL CYCLE G2 CHECKPOINT AND/OR AUGMENT THE ANTI-CANCER ACTIVITY OF DNA-DAMAGING TREATMENTS</B542><B541>fr</B541><B542>COMPOSES QUI SUPPRIMENT LE POINT DE CONTROLE G2 DU CYCLE CELLULAIRE INDUIT PAR L'ADN ENDOMMAGE ET/OU QUI ACCROIT L'ACTIVITE ANTI-CANCEREUSE DES TRAITEMENTS ENDOMMAGEANT L'ADN</B542></B540><B560><B561><text>EP-A- 0 409 728</text></B561><B561><text>WO-A-01/21771</text></B561><B561><text>WO-A-97/46228</text></B561><B561><text>WO-A-99/15157</text></B561><B561><text>WO-A-99/47522</text></B561><B561><text>WO-A-99/48495</text></B561><B561><text>DE-A- 2 049 865</text></B561><B561><text>US-A- 4 394 389</text></B561><B561><text>US-B1- 6 211 164</text></B561><B562><text>CHEMICAL ABSTRACTS, vol. 58, no. 6, 18 March 1963 (1963-03-18) Columbus, Ohio, US; abstract no. 5563c, K. C. JOSHI ET AL.: "Synthesis of fluorobenzoates as possible pesticides." page 5563; column 1; XP002266801 &amp; J. INDIAN CHEM. SOC., vol. 39, no. 7, 1962, pages 495-496,</text></B562><B562><text>CHEMICAL ABSTRACTS, vol. 58, no. 4, 18 February 1963 (1963-02-18) Columbus, Ohio, US; abstract no. 3341g, S. D. JOLAD ET AL.: "Substituted benzophenones." page 3341; column 1; XP002266802 &amp; J. KARNATAK UNIV., vol. 5, 1960, pages 1-9,</text></B562><B562><text>DATABASE CROSSFIRE BEILSTEIN [Online] BEILSTEIN INSTITUT ZUR FOEDERUNG DER CHEMISCHEN WISSENSCHAFTEN, FRANKFURT AM MAIN, DE; Database-Accession no. 2274611 (BRN), XP002266804 &amp; J. ORG. CHEM., vol. 41, 1976, page 2443</text></B562><B562><text>DATABASE CROSSFIRE BEILSTEIN [Online] BEILSTEIN INSTITUT ZUR FOEDERUNG DER CHEMISCHEN WISSENSCHAFTEN, FRANKFURT AM MAIN, DE; Database-Accession no. 2583565 (BRN), XP002266805 &amp; ARCH. PHARM. BER. DTSCH. PHARM. 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PIENTENPOL: "G2 Checkpoint and Anticancer Therapy" EUREKA, [Online] 25 January 2001 (2001-01-25), pages 1-28, XP002280757 Retrieved from the Internet: &lt;URL:http://www.eurekah.com/pietenpol/&gt; [retrieved on 2004-05-18]</text></B562><B562><text>ANTONIO M. SERAFIN ET AL.: "Chemosensitivity of prostatic tumour cell lines under conditions of G2 block abrogation" UROL RES, vol. 29, 2001, pages 221-227, XP002280758</text></B562><B562><text>PIERS EDWARD ET AL: "Improved Synthesis of Isogranulatimide, a G2 Checkpoint Inhibitor. Syntheses of Didemnimide C, Isodidemnimide A, Neodidemnimide A, 17-Methylgranulatimide, and Isogranulatimides A-C" JOURNAL OF ORGANIC CHEMISTRY, AMERICAN CHEMICAL SOCIETY. EASTON, US, vol. 65, 28 January 2000 (2000-01-28), pages 530-535, XP002175370 ISSN: 0022-3263</text></B562><B562><text>YULI WANG ET AL. : "Radiosensitization of p53 Mutant cells by PD0166285, a novel G2 checkpoint abrogator" CANCER RESEARCH., vol. 61, 15 November 2001 (2001-11-15), pages 8211-8217, XP002280759 AMERICAN ASSOCIATION FOR CANCER RESEARCH, BALTIMORE, MD., US ISSN: 0008-5472</text></B562></B560></B500><B700><B720><B721><snm>KAWABE, Takumi</snm><adr><str>1338-30 Okanomiya</str><city>Numazu,
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Shizuoka 410-0801</city><ctry>JP</ctry></adr></B731></B730><B740><B741><snm>Baldock, Sharon Claire</snm><sfx>et al</sfx><iid>100034649</iid><adr><str>Boult Wade Tennant 
Verulam Gardens 
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