(19)

(11)

EP 1 513 451 A1

(12)

(43) Date of publication: 16.03.2005 Bulletin 2005/11 (21) Application number: 03726926.3 (22) Date of filing: 21.05.2003

(51) International Patent Classification (IPC)7: A61B 8/02, A61B 8/06, A61B 8/12, A61B 5/02, A61B 5/00, A61B 8/00, A61B 8/14 (86) International application number: PCT/US2003/015820 (87) International publication number: WO 2003/099131 (04.12.2003 Gazette 2003/49)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 21.05.2002 US 381789 P 04.06.2002 US 384819 P (71) Applicant: New Health Sciences, Inc. Rockville, MD 20850 (US)	(72) Inventors: CRUTCHFIELD, Kevin, E. Potomac, MD 20854 (US) MOZAYENI, Robert, B. Rockville, MD 20852 (US) DAVIDSON, John Laytonsville, MD 20882 (US) FITALL, Simon Bethesda, MD 20814 (US) LALL, Rakesh Upper Marlboro, MD 20772 (US) (74) Representative: Crippa, Paolo Ernesto et al Jacobacci & Partners S.p.A.Via Senato 8 20121 Milano 20121 Milano (IT)