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(11)

EP 1 514 106 A1

(12)

(43) Date of publication: 16.03.2005 Bulletin 2005/11 (21) Application number: 03736779.4 (22) Date of filing: 29.05.2003

(51) International Patent Classification (IPC)7: G01N 33/53, A01N 37/18, A61K 38/00, C07K 1/00, C07K 2/00, C07K 4/00, C07K 5/00, C07K 7/00, C07K 14/00, C07K 16/00, C07K 17/00 (86) International application number: PCT/US2003/017211 (87) International publication number: WO 2003/102583 (11.12.2003 Gazette 2003/50)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 29.05.2002 US 384452 P 05.06.2002 US 386019 P 06.09.2002 US 408816 P 16.10.2002 US 272531 06.02.2003 US 445734 P (71) Applicant: ZyStor Therapeutics , Inc. Milwaukee, Wisconsin, 53202 (US)	(72) Inventors: LEBOWITZ, Jonathan, H. Frontenac, MO 63131 (US) BEVERLEY, Stephen, M. Clayton, MO 63105 (US) SLY, William, S. St. Louis, MO 63130 (US) (74) Representative: Chapman, Paul William et al Kilburn & Strode,20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)