(19)
(11) EP 1 515 718 A2

(12)

(88) Date of publication A3:
06.05.2004

(43) Date of publication:
23.03.2005 Bulletin 2005/12

(21) Application number: 03760087.1

(22) Date of filing: 16.06.2003
(51) International Patent Classification (IPC)7A61K 31/405, A61K 31/435, A61K 31/56, A61P 3/02, A61P 3/10, A61P 17/10
(86) International application number:
PCT/GB2003/002597
(87) International publication number:
WO 2003/105838 (24.12.2003 Gazette 2003/52)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 14.06.2002 GB 0213745

(71) Applicant: THE UNIVERSITY OF EDINBURGH
South Bridge,Edinburgh EH8 9YL (GB)

(72) Inventors:
  • WALKER, Brian Robert,University of Edinburgh
    Edinburgh EH4 2XU (GB)
  • ANDREW, Ruth,University of Edinburgh
    Edinburgh EH4 2XU (GB)

(74) Representative: Soames, Candida Jane 
D Young & Co120 Holborn
London EC1N 2DY
London EC1N 2DY (GB)

   


(54) MODULATION OF ACTIVATION OF GLUCOCORTICOID RECEPTORS BY BREAKDOWN PRODUCTS OF GLUCOCORTICOIDS