(19)
(11) EP 1 516 179 A1

(12)

(43) Date of publication:
23.03.2005 Bulletin 2005/12

(21) Application number: 02756335.2

(22) Date of filing: 26.06.2002
(51) International Patent Classification (IPC)7: G01N 33/00, G01N 33/53, A61K 39/395, A61K 39/42, A61K 39/40, A61K 38/00
(86) International application number:
PCT/US2002/020571
(87) International publication number:
WO 2004/003544 (08.01.2004 Gazette 2004/02)
(84) Designated Contracting States:
AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR
Designated Extension States:
AL LT LV MK RO SI

(71) Applicants:
  • Millennium Pharmaceuticals, Inc.
    Cambridge, MA 02139 (US)
  • Bundesrepublik Deutschlandletztvertreten durch DenDirektor des Robert-Koch-Instituts
    13353 Berlin (DE)

(72) Inventors:
  • ROTTMAN, James, B.
    Sudbury, MA 01776 (US)
  • KROCZEK, Richard
    13353 Berlin (DE)

(74) Representative: Jones Day 
Rechtsanwälte, Attorneys-at-Law, PatentanwältePrinzregentenstrasse 11
80538 München
80538 München (DE)

   


(54) METHODS AND COMPOSITIONS FOR THE DIAGNOSIS AND TREATMENT OF DEMYELINATING INFLAMMATORY DISORDERS