(19)
(11) EP 1 517 695 A2

(12)

(88) Date of publication A3:
29.12.2004

(43) Date of publication:
30.03.2005 Bulletin 2005/13

(21) Application number: 03742164.1

(22) Date of filing: 24.06.2003
(51) International Patent Classification (IPC)7: A61K 38/00, A61K 39/395, C12Q 1/00, C12Q 1/70, G01N 33/53, G01N 33/567
(86) International application number:
PCT/US2003/019864
(87) International publication number:
WO 2004/001014 (31.12.2003 Gazette 2004/01)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 25.06.2002 US 391035 P
16.10.2002 GB 0224017

(71) Applicant: Aventis Pharmaceuticals, Inc.
Bridgwater, New Jersey 08807-2854 (US)

(72) Inventors:
  • MERRILL, Jean
    Whippany, NJ 07981 (US)
  • PU, Su-Fen
    Bridgewater, NJ 08807 (US)
  • KHORKOVA, Olga
    North Haledon, NJ 07508 (US)
  • JI, Zhongqi
    Bridgewater, NJ 08807 (US)
  • CAMACHO, Fernando
    Union, NJ 07083 (US)
  • BUSCH, Steve
    Stewartsville, NJ 08806 (US)
  • WANG, Min
    Blue Bell, PA 19422 (US)
  • CHEN, Ting
    Bridgewater, NJ 08807 (US)
  • DINERSTEIN, Robert, J.
    Flemington, NJ 08822 (US)
  • YAO, Zhengbin
    Sugar Land, TX 77479 (US)
  • CHEN, Yangde
    Stewartsville, NJ 08886 (US)
  • ZHANG, Xin
    Piscataway, NJ 08854 (US)
  • CHANDROSS, Karen
    Somerset, NJ 08873 (US)
  • LEE, Lan
    Pluckemin, NJ 07978 (US)

(74) Representative: Löwrick, Oliver, Dr. 
Aventis Pharma Deutschland GmbH,Patent- und Lizenzabteilung
65926 Frankfurt am Main
65926 Frankfurt am Main (DE)

   


(54) OSTEOPONTIN, OLIGODENDROCYTES AND MYELINATION