(19)
(11) EP 1 517 702 A2

(12)

(88) Date of publication A3:
06.01.2005

(43) Date of publication:
30.03.2005 Bulletin 2005/13

(21) Application number: 03709214.5

(22) Date of filing: 21.02.2003
(51) International Patent Classification (IPC)7A61K 39/29, A61K 39/385, C12Q 1/70
(86) International application number:
PCT/US2003/005196
(87) International publication number:
WO 2003/102165 (11.12.2003 Gazette 2003/50)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 21.02.2002 US 80299
21.02.2002 US 82014
21.10.2002 US 274616

(71) Applicant: Apovia, Inc.
San Diego, CA 92121 (US)

(72) Inventor:
  • BIRKETT, Ashley, J.
    Escondido, CA 92027 (US)

(74) Representative: Fisher, Adrian John 
CARPMAELS & RANSFORD43-45 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) IMMUNOGENIC HBc CHIMER PARTICLES STABILIZED WITH AN N-TERMINAL CYSTEINE