(19)
(11)
EP 1 517 702 A2
(12)
(88)
Date of publication A3:
06.01.2005
(43)
Date of publication:
30.03.2005
Bulletin 2005/13
(21)
Application number:
03709214.5
(22)
Date of filing:
21.02.2003
(51)
International Patent Classification (IPC)
7
:
A61K
39/29
,
A61K
39/385
,
C12Q
1/70
(86)
International application number:
PCT/US2003/005196
(87)
International publication number:
WO 2003/102165
(
11.12.2003
Gazette 2003/50)
(84)
Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO
(30)
Priority:
21.02.2002
US 80299
21.02.2002
US 82014
21.10.2002
US 274616
(71)
Applicant:
Apovia, Inc.
San Diego, CA 92121 (US)
(72)
Inventor:
BIRKETT, Ashley, J.
Escondido, CA 92027 (US)
(74)
Representative:
Fisher, Adrian John
CARPMAELS & RANSFORD43-45 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)
(54)
IMMUNOGENIC HBc CHIMER PARTICLES STABILIZED WITH AN N-TERMINAL CYSTEINE