(19)
(11) EP 1 519 747 A2

(12)

(88) Date of publication A3:
03.02.2005

(43) Date of publication:
06.04.2005 Bulletin 2005/14

(21) Application number: 03721280.0

(22) Date of filing: 28.01.2003
(51) International Patent Classification (IPC)7A61K 39/42, A61K 39/395, C07K 14/00, C07K 16/00
(86) International application number:
PCT/US2003/002448
(87) International publication number:
WO 2003/064606 (07.08.2003 Gazette 2003/32)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT SE SI SK TR
Designated Extension States:
AL LT LV MK RO

(30) Priority: 28.01.2002 US 59989

(71) Applicant: Medarex, Inc.
Princeton, NJ 08540 (US)

(72) Inventors:
  • DEO, Yashwant, M.
    East Brunswick, NJ 08816 (US)
  • GRAZIANO, Robert
    Frenchtown, NJ 08825 (US)
  • HUDSON, Debra
    Livermore, CA 94550 (US)
  • HOLMES, Eric, H.
    Bothell, WA 98021 (US)
  • TINO, William, T.
    Redmond, WA 98052 (US)
  • BLACK, Amelia
    Los Gatos, CA 95035 (US)

(74) Representative: Lock, Graham James et al
Fry Heath & Spence LLPThe GablesMassetts Road
Horley,Surrey RH6 7DQ
Horley,Surrey RH6 7DQ (GB)

   


(54) HUMAN MONOCLONAL ANTIBODIES TO PROSTATE SPECIFIC MEMBRANE ANTIGEN (PSMA)