(19)
(11) EP 1 521 839 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
10.11.2010 Bulletin 2010/45

(45) Mention of the grant of the patent:
08.09.2010 Bulletin 2010/36

(21) Application number: 03740792.1

(22) Date of filing: 11.07.2003
(51) International Patent Classification (IPC): 
C12N 15/86(2006.01)
A61K 35/76(2006.01)
 C12N 5/10(2006.01)
A61K 48/00(2006.01)
(86) International application number:
PCT/GB2003/003012
(87) International publication number:
WO 2004/007735 (22.01.2004 Gazette 2004/04)

(54)

METHODS OF MAKING VIRAL PARTICLES HAVING A MODIFIED CELL BINDING ACTIVITY AND USES THEREOF

METHODE ZUR HERSTELLUNG VON VIRALEN PARTIKELN WELCHE EINE VERÄNDERTE ZELLBINDUNGSAKTIVITÄT HABEN UND DEREN VERWENDUNGEN

METHODES PERMETTANT D'OBTENIR DES PARTICULES PRESENTANT UNE ACTIVITE DE LIAISON CELLULAIRE MODIFIEE ET UTILISATIONS CORRESPONDANTES

(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

(30) Priority: 11.07.2002 GB 0216081

(43) Date of publication of application:
13.04.2005 Bulletin 2005/15

(73) Proprietor: Middlesex Higher Education Corporation
Hendon London NW4 4BT (GB)

(72) Inventor:
  • CASIMIR, Colin, Maurice
    London N2 9PT (GB)

(74) Representative: Wainwright, Jane Helen et al
Potter Clarkson LLP Park View House 58 The Ropewalk
Nottingham NG1 5DD
Nottingham NG1 5DD (GB)


(56) References cited: : 
WO-A-94/20621
 WO-A-97/12049
   
  • BITTNER ALEXANDRA ET AL: "Specific transduction of HIV-1 envelope expressing cells by retroviral vectors pseudotyped with hybrid CD4/CXCR4 receptors" JOURNAL OF VIROLOGICAL METHODS, vol. 104, no. 1, June 2002 (2002-06), pages 83-92, XP002259019 ISSN: 0166-0934
  • JIANG AN ET AL: "Cell-type-specific gene transfer into human cells with retroviral vectors that display single-chain antibodies" JOURNAL OF VIROLOGY, vol. 72, no. 12, December 1998 (1998-12), pages 10148-10156, XP002103152 ISSN: 0022-538X
  • LAVILLETTE DIMITRI ET AL: "Retargeting gene delivery using surface-engineered retroviral vector particles" CURRENT OPINION IN BIOTECHNOLOGY, vol. 12, no. 5, October 2001 (2001-10), pages 461-466, XP002259021 ISSN: 0958-1669
  • GOLLAN TIMOTHY J ET AL: "Redirecting retroviral tropism by insertion of short, nondisruptive peptide ligands into envelope" JOURNAL OF VIROLOGY, vol. 76, no. 7, April 2002 (2002-04), pages 3558-3563, XP002259022 ISSN: 0022-538X cited in the application
  • GOLLAN TIMOTHY J ET AL: "Selective targeting and inducible destruction of human cancer cells by retroviruses with envelope proteins bearing short peptide ligands" JOURNAL OF VIROLOGY, vol. 76, no. 7, April 2002 (2002-04), pages 3564-3569, XP002259023 ISSN: 0022-538X cited in the application
   
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