ATBECHDEDKESFRGBGRITLILUNLSEMCPTIE......FI....CY................................JDIM350 (Ver 2.1 Jan 2001) 1990850/0 1990110/0 1999001/0This application was filed on 08 - 11 - 2004 as a divisional application to the application mentioned under INID code 62.1522582CORRECTED EUROPEAN PATENT APPLICATIONA8A220050608W122DEBibliographieENBibliographyFRBibliographieEP04078076.92000010620041108EnEnEn990029819990107GB2005060820052320050413200515200506082005237 7C 12N 15/10 A 7C 12Q 1/68 BdeOptische SortiermethodeenOptical sorting methodfrTechnique de tri optiqueNONE00900080.3114127220000106MEDICAL RESEARCH COUNCIL0079145021465-202-01920 Park CrescentLondon W1N 4ALGBGriffiths, Andrew, MRC Lab. of Molecular BiologyMRC Centre, Hills RoadCambridge CB2 2QHGBTawfik, Dan0429 Magannai StreetJerusalem 96264ILSepp, Armin, Gendaq Limited1-3 Burtonhole Lane, Mill HillLondon NW7 1ADGBCrump, Julian Richard Johnet al00079223Mintz Levin Cohn Ferris Glovsky and Popeo Intellectual Property LLP The Rectory 9, Ironmonger LaneLondon EC2V 8EYGBATBECHCYDEDKESFIFRGBGRIEITLILUMCNLPTSE20050511200519

A method for increasing the concentration of a nucleic acid molecule comprising the steps of:

(a) forming aqueous microcapsules from a water-in-oil emulsion, wherein a plurality of microcapsules include a nucleic acid molecule, a bead capable of being linked to the nucleic acid molecule and an aqueous solution comprising components necessary to perform nucleic acid amplification;
(b) amplifying the nucleic acid molecule in the microcapsules to form amplified product copies of the nucleic acid molecule; and
(c) capturing the amplified product copies to the bead in the microcapsules; thereby increasing the concentration of the nucleic acid molecule.