(19)

(11)

EP 1 525 464 A2

(12)

(88) Date of publication A3: 25.03.2004 (43) Date of publication: 27.04.2005 Bulletin 2005/17 (21) Application number: 03760464.2 (22) Date of filing: 17.06.2003

(51) International Patent Classification (IPC)7: G01N 27/447, G01N 27/453 (86) International application number: PCT/US2003/019335 (87) International publication number: WO 2003/106973 (24.12.2003 Gazette 2003/52)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 18.06.2002 US 390259 P (71) Applicant: INVITROGEN CORPORATION Carlsbad, CA 92008 (US)	(72) Inventors: ROONEY, Regina, D. La Jolla, CA 92037 (US) SCOTT, Bradley, S. San Diego, CA 92128 (US) AMSHEY, Joseph, W. Encinitas, CA 92024 (US) JACKSON, Thomas, R. La Jolla, CA 92037 (US) ENGELHORN, Sheldon Cardiff, CA 92007 (US) (74) Representative: Dunlop, Hugh Christopher et al R G C Jenkins & Co.26 Caxton Street London SW1H 0RJ London SW1H 0RJ (GB)