(19)
(11) EP 1 527 062 A1

(12)

(43) Date of publication:
04.05.2005 Bulletin 2005/18

(21) Application number: 03765163.5

(22) Date of filing: 17.07.2003
(51) International Patent Classification (IPC)7C07D 309/10, C07D 405/06, C07D 405/14, A61K 31/351, A61P 25/22
(86) International application number:
PCT/GB2003/003098
(87) International publication number:
WO 2004/009573 (29.01.2004 Gazette 2004/05)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 23.07.2002 GB 0217068

(71) Applicant: MERCK SHARP & DOHME LTD.
Hoddesdon,Hertfordshire EN11 9BU (GB)

(72) Inventors:
  • DIRAT, Olivier
    Harlow, Essex CM20 2QR (GB)
  • ELLIOTT, Jason Matthew
    Harlow, Essex CM20 2QR (GB)
  • KULAGOWSKI, Janusz Jozef
    Harlow, Essex CM20 2QR (GB)
  • OWEN, Simon Neil
    Harlow, Essex CM20 2QR (GB)
  • RAUBO, Piotr Antoni
    Harlow, Essex CM20 2QR (GB)
  • SHAW, Duncan Edward
    Harlow, Essex CM20 2QR (GB)
  • WILLIAMS, Brian John
    Harlow, Essex CM20 2QR (GB)

(74) Representative: Man, Jocelyn 
Merck & Co.,Inc.,European Patent Department,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) TETRAHYDROPYRAN DERIVATIVES AND THEIR USE AS THERAPEUTIC AGENTS