(19)

(11)

EP 1 528 919 A2

(12)

(88) Date of publication A3: 01.07.2004 (43) Date of publication: 11.05.2005 Bulletin 2005/19 (21) Application number: 03784335.6 (22) Date of filing: 29.07.2003

(51) International Patent Classification (IPC)7: A61K 31/195, A61P 25/02, A61P 25/08, A61P 25/16, A61P 25/18, A61P 25/22, A61P 25/24, A61P 25/28, C07C 227/22 (86) International application number: PCT/IB2003/003193 (87) International publication number: WO 2004/014357 (19.02.2004 Gazette 2004/08)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 09.08.2002 GB 0218590 (71) Applicants: Pfizer Limited Sandwich,Kent CT13 9NJ (GB) GB  Maw, Graham Nigel Sandwich,Kent CT13 9NJ (GB) AT BE BG CH CY CZ DE DK EE ES FI FR GR HU IE IT LU MC NL PT	(72) Inventors: MAW, Graham Nigel Ramsgate Road,Sandwich,Kent CT13 9NJ (GB) RAWSON, David James Ramsgate Road,Sandwich,Kent CT13 9NJ (GB) THOMPSON, Lisa Rosemary Ramsgate Road,Sandwich,Kent, CT13 9NJ (GB) (74) Representative: Ruddock, Keith Stephen  Pfizer Limited,European Pharma Patent Department,Ramsgate Road Sandwich,Kent CT13 9NJ Sandwich,Kent CT13 9NJ (GB)