(19)
(11) EP 1 529 115 A2

(12)

(88) Date of publication A3:
17.03.2005

(43) Date of publication:
11.05.2005 Bulletin 2005/19

(21) Application number: 02749837.7

(22) Date of filing: 08.07.2002
(51) International Patent Classification (IPC)7C12Q 1/34, C12N 9/16, C07H 21/02, C07H 21/04
(86) International application number:
PCT/US2002/021461
(87) International publication number:
WO 2003/004621 (16.01.2003 Gazette 2003/03)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(30) Priority: 06.07.2001 US 303370 P
06.07.2001 US 303456 P
05.07.2002 US 190159

(71) Applicant: Elixir Pharmaceuticals, Inc.
Cambridge, MA 02139 (US)

(72) Inventors:
  • GUARENTE, Leonard
    Chestnut Hill, MA 02167 (US)
  • VAZIRI, Homayoun
    Somerville, MA 02144 (US)
  • IMAI, Shin-Ichiro
    St. Louis, MO 63146 (US)
  • GU, Wei
    Emerson, NJ 07630 (US)

(74) Representative: Ruffles, Graham Keith 
Marks & Clerk66-68 Hills Road
Cambridge,Cambridgeshire, CB2 1LA
Cambridge,Cambridgeshire, CB2 1LA (GB)

   


(54) SIR2 ACTIVITY