(19)

(11)

EP 1 529 118 A1

(12)

(43) Date of publication: 11.05.2005 Bulletin 2005/19 (21) Application number: 03787883.2 (22) Date of filing: 13.08.2003

(51) International Patent Classification (IPC)7: C12Q 1/68, C12N 15/12, C07K 14/465, C07K 16/18 (86) International application number: PCT/GB2003/003536 (87) International publication number: WO 2004/016812 (26.02.2004 Gazette 2004/09)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 14.08.2002 GB 0218955 (71) Applicant: ROSLIN INSTITUTE (EDINBURGH) Roslin,Midlothian EH25 9PS (GB)	(72) Inventor: CLINTON, Michael,Roslin Institute (Edinburgh) Midlothian EH25 9PS (GB) (74) Representative: Bassil, Nicholas Charles et al Kilburn & Strode20 Red Lion Street London WC1R 4PJ London WC1R 4PJ (GB)