(19)
(11) EP 1 529 120 A2

(12)

(88) Date of publication A3:
26.08.2004

(43) Date of publication:
11.05.2005 Bulletin 2005/19

(21) Application number: 03792234.1

(22) Date of filing: 28.07.2003
(51) International Patent Classification (IPC)7: C12Q 1/68
(86) International application number:
PCT/EP2003/008298
(87) International publication number:
WO 2004/018708 (04.03.2004 Gazette 2004/10)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 09.08.2002 EP 02017758

(71) Applicant: Bayer HealthCare AG
51368 Leverkusen (DE)

(72) Inventors:
  • SCHWERS, Stephan
    51061 Köln (DE)
  • KALLABIS, Harald
    51061 Köln (DE)
  • REIFENBERGER, Elke
    53757 Sankt Augustin (DE)
  • STROPP, Udo
    42781 Haan (DE)
  • SCHMITZ, Gerd
    93161 Sinzing (DE)

   


(54) GENETIC POLYMORPHISMS SENSITIVELY PREDICTING ADVERSE DRUG REACTIONS (ADR) AND DRUG EFFICACY