(19)
(11) EP 1 531 799 A1

(12)

(43) Date of publication:
25.05.2005 Bulletin 2005/21

(21) Application number: 03738952.5

(22) Date of filing: 10.06.2003
(51) International Patent Classification (IPC)7A61K 9/51, A61K 9/16, A61K 31/366, A61K 31/40, A61K 31/405, A61K 31/44, A61K 31/4025, A61K 31/4164, A61K 31/185, A61K 31/216, A61P 3/06, A61P 9/10, A61P 9/08, A61P 9/00, A61P 43/00, A61P 41/00
(86) International application number:
PCT/US2003/016206
(87) International publication number:
WO 2003/103640 (18.12.2003 Gazette 2003/51)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 10.06.2002 US 387404 P

(71) Applicant: Elan Pharma International Limited
Shannon,County Clare (IE)

(72) Inventors:
  • COOPER, Eugene, R.
    Berwyn, PA 19312 (US)
  • HOVEY, Douglas
    Trooper, PA 19403 (US)
  • CAREY, Greta
    Landsdale, PA 19446 (US)
  • LINDNER, Marie
    Radnor, PA 19087 (US)
  • LIVERSIDGE, Elaine
    West Chester, PA 19380 (US)
  • LIVERSIDGE, Gary, G.
    West Chester, PA 19380 (US)
  • RYDE, Tuula
    Malvern, PA 19355 (US)

(74) Representative: Wichmann, Hendrik, Dr. 
Isenbruck Bösl Hörschler Wichmann Huhn,Prinzregentenstrasse 68
81675 München
81675 München (DE)

   


(54) NANOPARTICULATE FORMULATIONS COMPRISING HMG COA REDUCTASE INHIBITOR DERIVATIVES ("STATINS"), NOVEL COMBINATIONS THEREOF AS WELL AS MANUFACTURING OF THESE PHARMACEUTICAL COMPOSITIONS