(19)
(11) EP 1 531 869 A2

(12)

(88) Date of publication A3:
02.09.2004

(43) Date of publication:
25.05.2005 Bulletin 2005/21

(21) Application number: 03792374.5

(22) Date of filing: 19.08.2003
(51) International Patent Classification (IPC)7: A61K 47/48, A61P 35/00, A61K 31/337, A61K 33/24
(86) International application number:
PCT/EP2003/009166
(87) International publication number:
WO 2004/018000 (04.03.2004 Gazette 2004/10)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 21.08.2002 EP 02018686

(71) Applicant: Boehringer Ingelheim International GmbH
55216 Ingelheim (DE)

(72) Inventors:
  • ADOLF, Günther
    A-1070 Wien (AT)
  • BAUM, Anke
    A-2534 Alland (AT)
  • HEIDER, Karl-Heinz
    A-2000 Stockerau (AT)

(74) Representative: Mahlbacher, Volker et al
Boehringer Ingelheim GmbH,CD Patents
55216 Ingelheim
55216 Ingelheim (DE)

   


(54) COMPOSITIONS AND METHODS FOR TREATING CANCER USING MAYTANSINOID CD44 ANTIBODY IMMUNOCONJUGATES AND CHEMOTHERAPEUTIC AGENTS