WHOLE BACTERIAL CELLS AS IMMUNE MODULATOR

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EP 1 534 330 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	04.06.2014 Bulletin 2014/23

(45)	Mention of the grant of the patent:
	12.03.2014 Bulletin 2014/11

(21)	Application number: 03793906.3

(22)	Date of filing: 05.09.2003

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International Patent Classification (IPC):

A61K 39/39^(2006.01)

A61K 39/04^(2006.01)

(86)	International application number:
	PCT/GB2003/003873

(87)	International publication number:
	WO 2004/022093 (18.03.2004 Gazette 2004/12)

(54)	WHOLE BACTERIAL CELLS AS IMMUNE MODULATOR GANZ-BAKTERIENZELLEN ALS IMMUNOMODULATOREN BACTERIES COMME MODULATEURS DE L'IMMUNITE

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
	Designated Extension States:
	AL LT LV MK

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Priority:

06.09.2002 GB 0220809
22.07.2003 GB 0317144

(43)	Date of publication of application:
	01.06.2005 Bulletin 2005/22

(73)	Proprietor: UCL Business PLC
	London W1T 4TP (GB)

(72)	Inventors:
	MCINTYRE, Graham Kent BR4 9BT (GB) STANFORD, John Lawson Kent TN12 9PE (GB) STANFORD, Cynthia Ann Kent TN12 9PE (GB) BOTTASSO, Oscar Adelmo Provincia de Santa Fe (AR)

(74)	Representative: Williams, Aylsa et al
	D Young & Co LLP 120 Holborn London EC1N 2DY London EC1N 2DY (GB)

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References cited: :

WO-A-02/32455
WO-A1-2007/071982

WO-A-98/39025

LEWIS D B: "Allergy immunotherapy and inhibition of Th2 immune responses: a sufficient strategy?" CURRENT OPINION IN IMMUNOLOGY, CURRENT BIOLOGY LTD, XX, vol. 14, no. 5, 1 October 2002 (2002-10-01), pages 644-651, XP004377421 ISSN: 0952-7915 cited in the application
CONFORTI ANITA ET AL: "Specific and long-lasting suppression of rat adjuvant arthritis by low-dose Mycobacterium butyricum", 19970101; 19970000, vol. 324, no. 2-3, 1 January 1997 (1997-01-01), pages 241-247, XP002319250,
Fiona Powrie ET AL: "Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunityin vivo", European Journal of Immunology, vol. 23, no. 11, 1 November 1993 (1993-11-01), pages 3043-3049, XP055054362, ISSN: 0014-2980, DOI: 10.1002/eji.1830231147
Fiona Powrie ET AL: "Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunity in vivo", European Journal of Immunology, vol. 23, no. 9, 1 September 1993 (1993-09-01), pages 2223-2229, XP055054363, ISSN: 0014-2980, DOI: 10.1002/eji.1830230926
Fiona Powrie ET AL: "Interleukin-4 and interleukin-10 synergize to inhibit cell-mediated immunityin vivo", European Journal of Immunology, vol. 23, no. 11, 1 November 1993 (1993-11-01), pages 3043-3049, XP055054365, ISSN: 0014-2980, DOI: 10.1002/eji.1830231147
ROOK G A ET AL: "The relevance to protection of three forms of delayed skin-test response evoked by m. leprae and other mycobacteria in mice. Correlation with the classical work in the guinea-pig.", PARASITE IMMUNOLOGY SUMMER 1979, vol. 1, no. 2, July 1979 (1979-07), pages 111-123, ISSN: 0141-9838
MOSMANN T R ET AL: "Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.", JOURNAL OF IMMUNOLOGY (BALTIMORE, MD. : 1950) 1 APR 1986, vol. 136, no. 7, 1 April 1986 (1986-04-01) , pages 2348-2357, ISSN: 0022-1767
STANFORD JOHN ET AL: "Immunotherapy with Mycobacterium vaccae in the treatment of tuberculosis.", FRONTIERS IN BIOSCIENCE : A JOURNAL AND VIRTUAL LIBRARY 1 MAY 2004, vol. 9, 1 May 2004 (2004-05-01), pages 1701-1719, ISSN: 1093-4715
HANSRANI MONICA ET AL: "Immunotherapy for the prevention of myointimal hyperplasia after experimental balloon injury of the rat carotid artery.", ANGIOLOGY JUL 2010, vol. 61, no. 5, July 2010 (2010-07), pages 437-442, ISSN: 1940-1574
MARRO ALICIA ET AL: "Successful immunotherapy of canine flea allergy with injected Actinomycetales preparations.", IMMUNOTHERAPY AUG 2011, vol. 3, no. 8, August 2011 (2011-08), pages 971-978, ISSN: 1750-7448
FAROOQI I S ET AL: "Early childhood infection and atopic disorder.", THORAX NOV 1998, vol. 53, no. 11, November 1998 (1998-11), pages 927-932, ISSN: 0040-6376


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	The file contains technical information submitted after the application was filed and not included in this specification

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