(19)

(11)

EP 1 534 429 A2

(12)

(88) Date of publication A3: 10.06.2004 (43) Date of publication: 01.06.2005 Bulletin 2005/22 (21) Application number: 03771636.2 (22) Date of filing: 16.07.2003

(51) International Patent Classification (IPC)7: B01L 3/00 (86) International application number: PCT/US2003/022226 (87) International publication number: WO 2004/011365 (05.02.2004 Gazette 2004/06)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 26.07.2002 US 398851 P 30.07.2002 US 399548 P 03.01.2003 US 366330 03.01.2003 US 336274 03.01.2003 US 336706 (71) Applicant: Applera Corporation Foster City, CA 94404 (US)	(72) Inventors: DESMOND, Sean, M. San Carlos, CA 94070 (US) SHIGEURA, John Portola Valley, CA 94028 (US) (74) Representative: Moran, Paula  OLSWANG90 High Holborn London WC1V 6XX London WC1V 6XX (GB)