ACTIVATION OF TUMOR-REACTIVE LYMPHOCYTES VIA ANTIBODIES OR GENES RECOGNIZING CD3 OR 4-1BB - Patent 1537219

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EP 1 537 219 A2

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(88)	Date of publication A3:
	14.04.2005

(43)	Date of publication:
	08.06.2005 Bulletin 2005/23

(21)	Application number: 03745635.7

(22)	Date of filing: 26.03.2003

(51)	International Patent Classification (IPC)⁷: C12N 15/85, C12N 15/86

(86)	International application number:
	PCT/US2003/009415

(87)	International publication number:
	WO 2003/083069 (09.10.2003 Gazette 2003/41)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
	Designated Extension States:
	AL LT LV MK

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Priority:

26.03.2002 US 107991

(71)	Applicant: Trubion Pharmaceuticals, Inc.
	Seattle, WA 98121 (US)

(72)	Inventors:
	LEDBETTER, Jeffrey, A. Shoreline, WA 98177 (US) HELLSTROM, Ingegerd Seattle, WA 98105 (US) HAYDEN-LEDBETTER, Martha Shoreline, WA 98177 (US) HELLSTROM, Karl Eric Seattle, WA 98105 (US)

(74)	Representative: Duckworth, Timothy John
	J.A. Kemp & Co.,14 South Square,Gray's Inn London WC1R 5JJ London WC1R 5JJ (GB)

(54)	ACTIVATION OF TUMOR-REACTIVE LYMPHOCYTES VIA ANTIBODIES OR GENES RECOGNIZING CD3 OR 4-1BB