(19)

(11)

EP 1 539 177 A2

(12)

(88) Date of publication A3: 29.07.2004 (43) Date of publication: 15.06.2005 Bulletin 2005/24 (21) Application number: 03750190.5 (22) Date of filing: 19.09.2003

(51) International Patent Classification (IPC)7: A61K 31/5375, A61K 31/353, A61K 31/343, A61K 31/352, A61P 9/00 (86) International application number: PCT/CA2003/001387 (87) International publication number: WO 2004/026285 (01.04.2004 Gazette 2004/14)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 19.09.2002 CA 2400254 (71) Applicants: Crackower, Michael A. Moorpark, CA 93021 (US) Penninger, Josef M. 1030 Vienna (AT) Amgen Canada Inc. Missisauga,Ontario L5N 7Y2 (CA)	(72) Inventor: The designation of the inventor has not yet been filed  () (74) Representative: Sonn & Partner Patentanwälte  Riemergasse 14 1010 Wien 1010 Wien (AT)