(19)

(11)

EP 1 539 232 A1

(12)

(43) Date of publication: 15.06.2005 Bulletin 2005/24 (21) Application number: 03794825.4 (22) Date of filing: 12.09.2003

(51) International Patent Classification (IPC)7: A61K 39/39, A61K 39/385, A61K 39/00, C07K 14/435, A61P 3/04 (86) International application number: PCT/DK2003/000592 (87) International publication number: WO 2004/024183 (25.03.2004 Gazette 2004/13)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 12.09.2002 DK 200201345 12.09.2002 US 410164 P (71) Applicant: Pharmexa A/S 2970 Horsholm (DK)	(72) Inventors: BOVING, Tine Elisabeth Gottschalk,Pharmexa A/S 2970 Horsholm (DK) KLYSNER, Steen,c/o Pharmexa A/S 2970 Horsholm (DK) (74) Representative: Inspicos A/S  Böge Allé 5,P.O. Box 45 2970 Hörsholm 2970 Hörsholm (DK)