(19)
(11) EP 1 539 246 A2

(12)

(88) Date of publication A3:
14.10.2004

(43) Date of publication:
15.06.2005 Bulletin 2005/24

(21) Application number: 03762973.0

(22) Date of filing: 09.05.2003
(51) International Patent Classification (IPC)7: A61K 48/00, A61K 38/23, A61K 38/21
(86) International application number:
PCT/US2003/014428
(87) International publication number:
WO 2004/004798 (15.01.2004 Gazette 2004/03)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 03.07.2002 WO PCT/US02/21335

(71) Applicants:
  • THE BRIGHAM AND WOMEN'S HOSPITAL, INC.
    Boston, MA 02115 (US)
  • BRANDEIS UNIVERSITY
    Waltham, MA 02154 (US)
  • CHILDREN'S MEDICAL CENTER CORPORATION
    BostonMassachusetts 02115 (US)
  • SYNTONIX PHARMACEUTICALS, INC.
    Waltham, MA 02451 (US)

(72) Inventors:
  • BLUMBERG, Richard, S.
    Chestnut Hill, MA 02167 (US)
  • LENCER, Wayne, I.
    Jamaica Plain, MA 02130 (US)
  • SIMISTER, Neil, E.
    Wellesley, MA 02482 (US)
  • BITONTI, Alan, J.
    Acton, MA 01720 (US)

(74) Representative: Jump, Timothy John Simon et al
Venner Shipley LLP20 Little Britain
London EC1A 7DH
London EC1A 7DH (GB)

   


(54) CENTRAL AIRWAY ADMINISTRATION FOR SYSTEMIC DELIVERY OF THERAPEUTICS