(19)

(11)

EP 1 539 997 A2

(12)

(88) Date of publication A3: 10.06.2004 (43) Date of publication: 15.06.2005 Bulletin 2005/24 (21) Application number: 03793209.2 (22) Date of filing: 21.08.2003

(51) International Patent Classification (IPC)7: C12Q 1/66, G01N 33/53 (86) International application number: PCT/US2003/026167 (87) International publication number: WO 2004/018996 (04.03.2004 Gazette 2004/10)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 21.08.2002 US 404972 P (71) Applicant: Rich, Ivan N. Columbia, SC 29213 (US)	(72) Inventor: Rich, Ivan N. Columbia, SC 29213 (US) (74) Representative: OK pat AG  Chamerstrasse 50 6300 Zug 6300 Zug (CH)