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EP 1 543 019 A2

(12)

(88) Date of publication A3: 29.04.2004 (43) Date of publication: 22.06.2005 Bulletin 2005/25 (21) Application number: 03794821.3 (22) Date of filing: 11.09.2003

(51) International Patent Classification (IPC)7: C07H 21/00, A61K 31/7052 (86) International application number: PCT/DK2003/000588 (87) International publication number: WO 2004/024757 (25.03.2004 Gazette 2004/13)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 11.09.2002 DK 200201334 19.11.2002 DK 200201786 20.12.2002 DK 200201956 16.04.2003 DK 200300600 (71) Applicant: Santaris Pharma A/S 2970 Horsholm (DK)

(72) Inventors: RASMUSSEN, Palle DK-2880 Bagsvaerd (DK) FRANDSEN, Niels, Montano DK-2100 Copenhagen (DK) NYBORG, Marlene DK-1920 Frederiksberg C (DK) RASMUSSEN, Frank, Winther DK-1620 Copenhagen V (DK) HAMZAVI, Ramin DK-2400 Copenhagen NV (DK) NIELSEN, Peter, Eigild DK-2980 Kokkedal (DK) KJAERULFF, Soren DK-2840 Holte (DK) (74) Representative: Olsen, Lars Pallisgaard et al Zacco Denmark A/SHans Bekkevolds Allé 7 2900 Hellerup 2900 Hellerup (DK)