ATBECHDEDKESFRGBGRITLILUNLSEMCPTIESI....FI....CY..TRBGCZEEHU..SK....................................JDIM360 Ver 2.40 (30 Jan 2013) - 2999001/0201401131544294CORRECTED EUROPEAN PATENT SPECIFICATIONB8B120140319W172deBibliographieenBibliographyfrBibliographieEP03707180.0200302282005021620100630jaenen200220856820020717JP2014031920141220050622200525201304102013152012062520130410AT20130410BE20130710BG20130410CY20130410CZ20130410DK20130410EE20130721ES20130410FI20130711GR20130410IT20130410NL20130812PT20130410SE20130410SI20130410SK20140319201412C12N 15/09 20060101AFI20040131BHEP C07H 7/06 20060101ALI20040131BHEP C07H 11/04 20060101ALI20040131BHEP deNUKLEOSIDE UND NUKLEOTIDE MIT NEUEN UNNATÜRLICHEN BASEN UND VERWENDUNG DAVONenNUCLEOSIDES OR NUCLEOTIDES HAVING NOVEL UNNATURAL BASES AND USE THEREOFfrNUCLEOSIDE OU NUCLEOTIDE AYANT UNE NOUVELLE BASE NON NATURELLE ET SON UTILISATIONWO-A-01/16149T. OHTSUKI ET AL.: "Unnatural base pairs for specific transcription" PNAS, vol. 98, 2001, pages 4922-4925, XP002546129SILVERMAN D B ET AL: "MOLECULAR MOMENT SIMILARITY BETWEEN SEVERAL NUCLEOSIDE ANALOGS OF THYMIDINE AND THYMIDINE" JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS, ADENINE PRESS, NEW YORK, NY, US, vol. 16, no. 6, 1 June 1999 (1999-06-01), pages 1169-1175, XP009050925 ISSN: 0739-1102ICHIRO HIRAO ET AL.: 'Jinko enkitai no sosei iden ango no kakucho o mezashite' PROTEIN, NUCLEIC ACID AND ENZYME vol. 47, no. 14, November 2002, pages 1904 - 1913, XP002974101HIRAO I. ET AL.: 'A unique unnatural base pair between a C analogue, pseudoisocytosine and an A analogue, 6-methoxypurine, in replication' BIOORGANIC & MEDICINAL CHEMISTRY LETTERS vol. 12, May 2002, pages 1391 - 1393, XP002974102FUJIWARA T. ET AL.: 'Synthesis of 6-(2-thienyl) purine nucleoside derivatives that form unnatural base pairs with pyridin-2-one nucleosides' BIOORGANIC & MEDICINAL CHEMISTRY LETTERS vol. 11, 2001, pages 2221 - 2223, XP002974103HIRANO I. ET AL.: 'An unnatural base pair for incorporating amino acids analogs into proteins' NATURE BIOTECH. vol. 20, February 2002, pages 177 - 182, XP00106846620090928HIRAO, Ichiro,c/o RIKEN 2-1, HirosawaWako-shi, Saitama 351-0198JPYOKOYAMA, Shigeyuki,c/o Riken, Yokohama Institute 1-7-22, Suehiro-cho, Tsurumi-kuYokohama-shi, Kanagawa 230-0045JPHIRAO, Michiko,c/o RIKEN 2-1, HirosawaWako-shi, Saitama 351-0198JPMITSUI, Tsuneo1-3-3-502, ChuoWako-shi, Saitama 351-0198JPRIKEN100208813CMD/FP62835012-1, HirosawaWako-shi, Saitama 351-0198JPJapan Science and Technology Agency100151381CMD/FP62835011-8, Honcho 4-chomeKawaguchi-shi, Saitama 332-0012JPDenison, Christopher Marcuset al100046730Mewburn Ellis LLP 33 Gutter LaneLondon EC2V 8ASGBATBEBGCHCYCZDEDKEEESFIFRGBGRHUIEITLILUMCNLPTSESISKTRJP200300234220030228jaWO20040077132004012220040420050622200525