(19)

(11)

EP 1 545 493 A2

(12)

(88) Date of publication A3: 24.02.2005 (43) Date of publication: 29.06.2005 Bulletin 2005/26 (21) Application number: 03767196.3 (22) Date of filing: 05.08.2003

(51) International Patent Classification (IPC)7: A61K 31/21, A61K 31/26 (86) International application number: PCT/US2003/024455 (87) International publication number: WO 2004/012677 (12.02.2004 Gazette 2004/07)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 05.08.2002 US 401130 P (71) Applicant: Wackvom Limited IS-Tortola (VG)	(72) Inventors: WONG, Kin-Ping Fresno, CA 93720 (US) WONG, Ming-Chung San Diego, CA 92130 (US) REN, Dai Fresno, CA 93710 (US) (74) Representative: Gervasi, Gemma, Dr. et al Notarbartolo & Gervasi GmbH,Bavariaring 21 80336 München 80336 München (DE)