(19)
(11) EP 1 545 551 A1

(12)

(43) Date of publication:
29.06.2005 Bulletin 2005/26

(21) Application number: 02768820.9

(22) Date of filing: 06.09.2002
(51) International Patent Classification (IPC)7: A61K 31/66, A61K 31/553
(86) International application number:
PCT/US2002/028519
(87) International publication number:
WO 2004/022069 (18.03.2004 Gazette 2004/12)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(71) Applicants:
  • Durect Corporation
    Cupertino, CA 95014 (US)
  • Puel, Jean-Luc
    Le Ramasol, 34660 Cournonterral (FR)
  • Pujol, Rémy
    34510 Florensac (FR)
  • Christen, Yves
    75116 Paris (FR)
  • INSTITUT NATIONAL DE LA SANTE ET DE LARECHERCHE MEDICALE (INSERM)
    75013 Paris (FR)

(72) Inventors:
  • PUEL, Jean-Luc
    F-34660 Cournonterral (FR)
  • PUJOL, Rémy
    F-34510 Florensac (FR)
  • CHRISTEN, Yves
    F-75116 Paris (FR)

(74) Representative: Woods, Geoffrey Corlett et al
J.A. KEMP & CO.Gray's Inn14 South Square
London WC1R 5JJ
London WC1R 5JJ (GB)

   


(54) DELIVERY OF MODULATORS OF GLUTAMATE-MEDIATED NEUROTRANSMISSION TO THE INNER EAR