(19)

(11)

EP 1 551 383 A2

(12)

(88) Date of publication A3: 28.10.2004 (43) Date of publication: 13.07.2005 Bulletin 2005/28 (21) Application number: 03742158.3 (22) Date of filing: 24.06.2003

(51) International Patent Classification (IPC)7: A61K 31/195, C12Q 1/68 (86) International application number: PCT/US2003/019831 (87) International publication number: WO 2004/000228 (31.12.2003 Gazette 2004/01)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 24.06.2002 US 391345 P 25.10.2002 US 421218 P 26.11.2002 US 429142 P 31.03.2003 US 458935 P (71) Applicant: Paratek Pharmaceuticals, Inc. Boston, MA 02111 (US)	(72) Inventors: ALEKSHUN, Michael, N. Wakefield, MA 01880 (US) LEVY, Stuart, B. Boston, MA 02116 (US) (74) Representative: Nash, David Allan et al HASELTINE LAKE,Redcliff Quay120 Redcliff Street Bristol BS1 6HU Bristol BS1 6HU (GB)