4-AMINO-AZEPAN-3-ONE COMPOUNDS AS CATHEPSIN K INHIBITORS USEFUL IN THE TREATMENT OF OSTEOPOROSIS - Patent 1551823

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EP 1 551 823 A1

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(43)	Date of publication:
	13.07.2005 Bulletin 2005/28

(21)	Application number: 03757604.8

(22)	Date of filing: 07.10.2003

(51)	International Patent Classification (IPC)⁷: C07D 401/12, A61K 31/55, A61P 19/08

(86)	International application number:
	PCT/CA2003/001551

(87)	International publication number:
	WO 2004/033445 (22.04.2004 Gazette 2004/17)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
	Designated Extension States:
	AL LT LV MK

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Priority:

08.10.2002 US 416892 P

(71)	Applicant: MERCK FROSST CANADA INC.
	Kirkland,Quebec H9H 3L1 (CA)

(72)	Inventor:
	BLACK, Cameron Kirkland, Québec H9H 3L1 (CA)

(74)	Representative: Buchan, Gavin MacNicol
	Merck & Co., Inc.,European Patent Department,Terlings Park,Eastwick Road Harlow,Essex CM20 2QR Harlow,Essex CM20 2QR (GB)

(54)	4-AMINO-AZEPAN-3-ONE COMPOUNDS AS CATHEPSIN K INHIBITORS USEFUL IN THE TREATMENT OF OSTEOPOROSIS