(19)
(11) EP 1 551 836 A1

(12)

(43) Date of publication:
13.07.2005 Bulletin 2005/28

(21) Application number: 02807881.4

(22) Date of filing: 04.10.2002
(51) International Patent Classification (IPC)7C07D 471/10, A61K 31/435, A61P 25/00, A61P 29/00
(86) International application number:
PCT/GB2002/004515
(87) International publication number:
WO 2004/031190 (15.04.2004 Gazette 2004/16)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR IE IT LI LU MC NL PT SE SK TR
Designated Extension States:
AL LT LV MK RO SI

(71) Applicant: MERCK SHARP & DOHME LTD.
Hoddesdon,Hertfordshire EN11 9BU (GB)

(72) Inventors:
  • Kulagowski, Janusz Jozef
    Harlow,Essex CM20 2QR (GB)
  • Raubo, Piotr Antoni
    Harlow,Essex CM20 2QR (GB)
  • Thomson, Christopher George
    Harlow,Essex CM20 2QR (GB)

(74) Representative: Man, Jocelyn 
Merck & Co.,Inc.,European Patent Department,Terlings Park,Eastwick Road
Harlow,Essex CM20 2QR
Harlow,Essex CM20 2QR (GB)

   


(54) AZABICYCLIC AMINE DERIVATIVES AS NK-1 RECEPTOR ANTAGONISTS