(19)
(11) EP 1 551 841 A1

(12)

(43) Date of publication:
13.07.2005 Bulletin 2005/28

(21) Application number: 03765825.9

(22) Date of filing: 21.07.2003
(51) International Patent Classification (IPC)7C07D 487/04, C07D 519/00, A61K 31/519, A61P 3/10
// (C07D487/04, 239:00), C07D231:00
(86) International application number:
PCT/US2003/022716
(87) International publication number:
WO 2004/009602 (29.01.2004 Gazette 2004/05)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 23.07.2002 US 397988 P

(71) Applicant: SmithKline Beecham Corporation
Philadelphia, PA 19103 (US)

(72) Inventors:
  • BROWN, Matthew, Lee
    Indianapolis, IN 46202 (US)
  • CHEUNG, MuiGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • DICKERSON, Scott, HowardGlaxoSmithKline
    Reseach Triangle Park, NC 27709 (US)
  • GARRIDO, Dulce, MariaGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • MILLS, Wendy, YoonGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • MIYAZAKI, Yasushi
    Tsukuba-shi, Ibaraki Pref 300-4247 (JP)
  • PEAT, Andrew, JamesGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • PECKHAM, Jennifer, PooleGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • SMALLEY, Terrence, LGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • THOMSON, Stephen, AndrewGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)
  • VEAL, James, Marvin
    Apex, NC 27502 (US)
  • WILSON, Jayme, Lyn, RoarkGlaxoSmithKline
    Research Triangle Park, NC 27709 (US)

(74) Representative: Learoyd, Stephanie Anne 
GlaxoSmithKlineCorporate Intellectual Property (CN9.25.1)980 Great West Road
Brentford, Middlesex TW8 9GS
Brentford, Middlesex TW8 9GS (GB)

   


(54) PYRAZOLOPYRIMIDINES AS KINASE INHIBITORS