(19)
(11) EP 1 551 964 A2

(12)

(88) Date of publication A3:
19.05.2005

(43) Date of publication:
13.07.2005 Bulletin 2005/28

(21) Application number: 03788377.4

(22) Date of filing: 08.08.2003
(51) International Patent Classification (IPC)7C12N 9/12, C12N 1/20, C12Q 1/00, C12Q 1/58, C07H 21/04, A01N 25/00
(86) International application number:
PCT/US2003/025016
(87) International publication number:
WO 2004/016726 (26.02.2004 Gazette 2004/09)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 09.08.2002 US 402254 P
22.11.2002 US 428614 P

(71) Applicant: THE PRESIDENT AND FELLOWS OF HARVARD COLLEGE
Cambridge, MA 02114 (US)

(72) Inventors:
  • SINCLAIR, David, A.
    West Roxbury, MA 02132 (US)
  • BITTERMAN, Kevin, J.
    Boston, MA 02115 (US)

(74) Representative: Lee, Nicholas John et al
Haseltine Lake & Co.,Imperial House,15-19 Kingsway
London WC2B 6UD
London WC2B 6UD (GB)

   


(54) METHODS AND COMPOSITIONS FOR EXTENDING THE LIFE SPAN AND INCREASING THE STRESS RESISTANCE OF CELLS AND ORGANISMS