(19)

(11)

EP 1 552 008 A1

(12)

(43) Date of publication: 13.07.2005 Bulletin 2005/28 (21) Application number: 03765475.3 (22) Date of filing: 30.06.2003

(51) International Patent Classification (IPC)7: C12Q 1/68, C07H 21/02, A61K 9/14 (86) International application number: PCT/US2003/020544 (87) International publication number: WO 2004/009848 (29.01.2004 Gazette 2004/05)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 24.07.2002 US 205195 (71) Applicant: LI, Xing-Xiang Vienna, VA 22182 (US)	(72) Inventor: LI, Xing-Xiang Vienna, VA 22182 (US) (74) Representative: Klunker . Schmitt-Nilson . Hirsch  Winzererstrasse 106 80797 München 80797 München (DE)