(19)
(11) EP 1 552 310 A2

(12)

(88) Date of publication A3:
22.07.2004

(43) Date of publication:
13.07.2005 Bulletin 2005/28

(21) Application number: 03785626.7

(22) Date of filing: 16.10.2003
(51) International Patent Classification (IPC)7: G01N 33/68, C12Q 1/48, C12N 9/12, A01K 67/027, C12N 15/00, A61K 38/45, C07K 16/40
(86) International application number:
PCT/EP2003/011478
(87) International publication number:
WO 2004/035823 (29.04.2004 Gazette 2004/18)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 17.10.2002 EP 02023272
17.10.2002 US 418721 P

(71) Applicant: EVOTEC Neurosciences GmbH
22525 Hamburg (DE)

(72) Inventors:
  • VON DER KAMMER, Heinz
    22607 Hamburg (DE)
  • POHLNER, Johannes
    22175 Hamburg (DE)

(74) Representative: von Kreisler Selting Werner 
PatentanwälteP.O. Box 10 22 41
50462 Köln
50462 Köln (DE)

   


(54) DIAGNOSTIC AND THERAPEUTIC USE OF THE NICOTINAMIDE MONONUCLEOTIDE ADENYLYLTRANSFERASE 2 (NMNAT-2) GENE AND PROTEIN FOR NEURODEGENERATIVE DISEASES