(19)
(11) EP 1 556 682 B8

(12) CORRECTED EUROPEAN PATENT SPECIFICATION
Note: Bibliography reflects the latest situation

(15) Correction information:
Corrected version no 1 (W1 B1)

(48) Corrigendum issued on:
17.02.2010 Bulletin 2010/07

(45) Mention of the grant of the patent:
07.10.2009 Bulletin 2009/41

(21) Application number: 03809590.7

(22) Date of filing: 20.10.2003
(51) International Patent Classification (IPC): 
G01N 33/68(2006.01)
G01N 33/532(2006.01)
G01N 33/542(2006.01)
(86) International application number:
PCT/US2003/033262
(87) International publication number:
WO 2004/038369 (06.05.2004 Gazette 2004/19)

(54)

IP3 PROTEIN BINDING ASSAY

IP3-PROTEIN-BINDUNGSTEST

BIODOSAGE DE IP3 PAR LIASON DE PROTEINE


(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

(30) Priority: 21.10.2002 US 420469 P

(43) Date of publication of application:
27.07.2005 Bulletin 2005/30

(73) Proprietor: DiscoveRx Corporation
Fremont, CA 94538 (US)

(72) Inventors:
  • NAQVI, Tabassum
    Fremont, CA 94538 (US)
  • ROUHANI, Riaz
    Concord, CA 94521 (US)
  • FUNG, Peter
    Sunnyvale, CA 94086 (US)
  • EGLEN, Richard
    Los Altos, CA 94024 (US)
  • SINGH, Rajendra
    San Jose, CA 95135 (US)

(74) Representative: Sexton, Jane Helen 
J.A. Kemp & Co. 14 South Square Gray's Inn
London WC1R 5JJ
London WC1R 5JJ (GB)


(56) References cited: : 
EP-A2- 0 992 587
US-A- 5 977 311
US-A- 5 252 707
   
  • BOSSE R ET AL: "RAPID AND ULTRA-SENSITIVE DETECTION OF CAMP AND IP3 USING THE HOMOGENEOUS AND NON-RADIOACTIVE PLATFORM ALPHASCREEN" FASEB JOURNAL (FEDERATION OF AMERICAN SOCIETIES FOR EXPERIMENTAL BIOLOGY), BETHESDA, US, vol. 16, no. 4, 4 March 2002 (2002-03-04), page A575, XP009022719 ISSN: 0892-6638
  • ROSSI F ET AL: "MONITORING PROTEIN-PROTEIN INTERACTIONS IN INTACT EUKARYOTIC CELLS BY BETA-GALACTOSIDASE COMPLEMENTATION" PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 94, August 1997 (1997-08), pages 8405-8410, XP002064565 ISSN: 0027-8424
  • DATABASE BIOSIS [Online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1990, HIRATA M ET AL: "STEREOSPECIFIC RECOGNITION OF INOSITOL 1 4 5-TRISPHOSPHATE ANALOGS BY THE PHOSPHATASE KINASE AND BINDING PROTEINS" XP002411337 Database accession no. PREV199090036981 & JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 265, no. 15, 1990, pages 8404-8407, ISSN: 0021-9258
  • RILEY ANDREW M ET AL: "Interactions of inositol 1,4,5-trisphosphate (IP3) receptors with synthetic poly(ethylene glycol)-linked dimers of IP3 suggest close spacing of the IP3-binding sites." JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 277, no. 43, 25 October 2002 (2002-10-25), pages 40290-40295, XP002411424 ISSN: 0021-9258
  • PERKINELMER LIFE SCIENCES: "Performing AlphaScreen IP3 Functional Assay" 31 July 2002 (2002-07-31), , XP002412571 * pages 2-3 *
   
Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).