SPLEEN TYROSINE KINASE CATALYTIC DOMAIN: CRYSTAL STRUCTURE AND BINDING POCKETS THEREOF - Patent 1558753

(19)

(11)

EP 1 558 753 A2

(12)

(88)	Date of publication A3:
	07.04.2005

(43)	Date of publication:
	03.08.2005 Bulletin 2005/31

(21)	Application number: 03809070.0

(22)	Date of filing: 16.10.2003

(51)	International Patent Classification (IPC)⁷: C12Q 1/48, C12N 9/12, G06F 19/00

(86)	International application number:
	PCT/US2003/032812

(87)	International publication number:
	WO 2004/035604 (29.04.2004 Gazette 2004/18)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
	Designated Extension States:
	AL LT LV MK

(30)

Priority:

16.10.2002 US 419382 P

(71)	Applicant: Millennium Pharmaceuticals, Inc.
	Cambridge, MA 02139 (US)

(72)	Inventors:
	WILLIAMS, David, H. Cambridge CB2 4EE (GB) LAMERS, Maria, Bardina, Antonia, Cornelia Cambridge CB1 6FD (GB) SMITH, Stephanie Belper, Derbyshire DE56 1TU (GB) CHERRY, Michael Cambridge CB2 4EE (GB)

(74)	Representative: VOSSIUS & PARTNER
	Siebertstrasse 4 81675 München 81675 München (DE)

(54)	SPLEEN TYROSINE KINASE CATALYTIC DOMAIN: CRYSTAL STRUCTURE AND BINDING POCKETS THEREOF