PROCESS FOR THE PREPARATION OF GLATIRAMER ACETATE BY POLYMERISATION OF N-CARBOXY ANHYDRIDES OF L-ALANINE, L-TYROSINE, BENZYL L-GLUTAMATE AND BENZYLOXYCARBONYL L-LYSINE - Patent 1565486

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EP 1 565 486 A2

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(88)	Date of publication A3:
	07.10.2004

(43)	Date of publication:
	24.08.2005 Bulletin 2005/34

(21)	Application number: 03775017.1

(22)	Date of filing: 13.11.2003

(51)	International Patent Classification (IPC)⁷: C07K 14/00, C07K 1/06

(86)	International application number:
	PCT/CA2003/001744

(87)	International publication number:
	WO 2004/043995 (27.05.2004 Gazette 2004/22)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
	Designated Extension States:
	AL LT LV MK

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Priority:

13.11.2002 CA 2411786
24.12.2002 US 326994

(71)	Applicant: Apotex Pharmachem Inc.
	Ontario N3T 6B8 (CA)

(72)	Inventors:
	BEJAN, Elena Brantford, Ontario N3R 7W6 (CA) WEERATUNGA, Gamini Brantford, Ontario N3P 1R1 (CA) HORNE, Stephen, E. Burlington, Ontario L7R 1R5 (CA)

(74)	Representative: Howard, Paul Nicholas et al
	Carpmaels & Ransford, 43-45 Bloomsbury Square London WC1A 2RA London WC1A 2RA (GB)

(54)	PROCESS FOR THE PREPARATION OF GLATIRAMER ACETATE BY POLYMERISATION OF N-CARBOXY ANHYDRIDES OF L-ALANINE, L-TYROSINE, BENZYL L-GLUTAMATE AND BENZYLOXYCARBONYL L-LYSINE