CYANOGUANIDINES AND CYANOAMIDINES AS ERBB2 AND EGFR INHIBITORS - Patent 1567506

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(11)

EP 1 567 506 A2

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(88)	Date of publication A3:
	16.09.2004

(43)	Date of publication:
	31.08.2005 Bulletin 2005/35

(21)	Application number: 03768789.4

(22)	Date of filing: 10.11.2003

(51)	International Patent Classification (IPC)⁷: C07D 239/94, C07D 215/42, A61K 31/517, A61K 31/4706, A61P 31/18

(86)	International application number:
	PCT/US2003/035670

(87)	International publication number:
	WO 2004/046101 (03.06.2004 Gazette 2004/23)

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
	Designated Extension States:
	AL LT LV MK

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Priority:

20.11.2002 US 427544 P

(71)	Applicant: Array Biopharma, Inc.
	Boulder, CO 80301 (US)

(72)	Inventors:
	WALLACE, Eli Lyons, CO 80540 (US) TOPALOV, George Superior, CO 80027 (US) ZHAO, Qian Superior, CO 80027 (US) LYSSIKATOS, Joseph P. Superior, CO 80027 (US)

(74)	Representative: Gillard, Richard Edward et al
	Elkington and Fife LLP, Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR Kent TN13 1XR (GB)

(54)	CYANOGUANIDINES AND CYANOAMIDINES AS ERBB2 AND EGFR INHIBITORS