(19)
(11) EP 1 569 897 A1

(12)

(43) Date of publication:
07.09.2005 Bulletin 2005/36

(21) Application number: 03809577.4

(22) Date of filing: 17.10.2003
(51) International Patent Classification (IPC)7C07C 323/52, C07C 275/34, C07C 275/28, A61K 31/196, A61P 3/06, A61P 9/10, A61P 9/12
(86) International application number:
PCT/US2003/033090
(87) International publication number:
WO 2004/037778 (06.05.2004 Gazette 2004/19)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 21.10.2002 US 419935 P
15.08.2003 US 495270 P

(71) Applicant: JANSSEN PHARMACEUTICA N.V.
2340 Beerse (BE)

(72) Inventors:
  • CHEN, Xiaoli
    Belle Mead, NJ 08502 (US)
  • MATTHEWS, Jay, M.
    Lansdale, PA 19446 (US)
  • LEE, Jung
    Ambler, PA 19002 (US)
  • RYBCZYNSKI, Philip
    Branchburg, NJ 08876 (US)
  • DEMAREST, Keith T.
    NJ 08822 (US)

(74) Representative: Fisher, Adrian John et al
CARPMAELS & RANSFORD 43-45 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) SUBSTITUTED TETRALINS AND INDANES