(19)
(11) EP 1 572 129 A2

(12)

(43) Date of publication:
14.09.2005 Bulletin 2005/37

(21) Application number: 03757414.2

(22) Date of filing: 09.06.2003
(51) International Patent Classification (IPC)7A61K 7/00
(86) International application number:
PCT/US2003/017992
(87) International publication number:
WO 2003/103598 (18.12.2003 Gazette 2003/51)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 07.06.2002 US 387001 P

(71) Applicants:
  • UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL
    Chapel Hill, NC 27599-4105 (US)
  • GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC.
    Atlanta, GA 30303-3083 (US)
  • Tidwell, Richard R.
    Pittsboro, NC 27312lina (US)
  • Boykin, David
    Atlanta, GA 30315 (US)
  • Chalifour, Robert J.
    Quebec H9C 1T4 (CA)
  • Kong, Xianqi
    Quebec H9B 3J7 (CA)

(72) Inventors:
  • TIDWELL, Richard R.
    Pit tsboro, NC 27312 (US)
  • BOYKIN, David
    Atlanta, GA 30315 (US)
  • CHALIFOUR, Robert, J.
    Ile Bizard, Québec H9C 1T4 (CA)
  • KONG, Xianqi
    Dollard-des-Ormeaux, Québec H9B 3J7 (CA)
  • WU, Xinfu
    Dollard-des-Ormeaux, Québec H9B 1Y4 (CA)
  • LU, Wenshuo
    Montreal, Québec H3S 1S4 (CA)

(74) Representative: Behnisch, Werner et al
Reinhard-Skuhra-Weise & Partner GbR, Friedrichstrasse 31
80801 München
80801 München (DE)

   


(54) AMIDINE DERIVATIVES FOR TREATING AMYLOIDOSIS