(19)

(11)

EP 1 575 523 A1

(12)

(43) Date of publication: 21.09.2005 Bulletin 2005/38 (21) Application number: 03814199.0 (22) Date of filing: 17.12.2003

(51) International Patent Classification (IPC)7: A61K 6/10 (86) International application number: PCT/US2003/040534 (87) International publication number: WO 2004/058196 (15.07.2004 Gazette 2004/29)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR (30) Priority: 23.12.2002 US 436030 P (71) Applicant: DENTSPLY INTERNATIONAL, INC. York, PA 17405-0872 (US)	(72) Inventors: HARE, Robert, V. Georgetown, DE 19947 (US) HAMMESFAHR, Paul, D. Wyoming, DE 19934 (US) (74) Representative: Hartz, Nikolai  Wächtershauser & Hartz Weinstrasse 8 80333 München 80333 München (DE)