BORRELIDIN-DERIVATIVES AND THEIR USE IN MEDICINE

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EP 1 576 160 B8

(12)	CORRECTED EUROPEAN PATENT SPECIFICATION
	Note: Bibliography reflects the latest situation

(15)	Correction information:
	Corrected version no 1 (W1 B1)

(48)	Corrigendum issued on:
	27.06.2007 Bulletin 2007/26

(45)	Mention of the grant of the patent:
	02.05.2007 Bulletin 2007/18

(21)	Application number: 03786170.5

(22)	Date of filing: 24.12.2003

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International Patent Classification (IPC):

C07D 313/00^(2006.01)
A61P 33/06^(2006.01)
A61P 35/00^(2006.01)
A61P 19/02^(2006.01)

A61K 31/335^(2006.01)
A61P 17/06^(2006.01)
A61P 9/10^(2006.01)

(86)	International application number:
	PCT/GB2003/005704

(87)	International publication number:
	WO 2004/058976 (15.07.2004 Gazette 2004/29)

(54)	BORRELIDIN-DERIVATIVES AND THEIR USE IN MEDICINE BORRELIDIN-DERIVATE UND IHRE MEDIZINISCHE ANWENDUNG DERIVES DE BORRELIDINE ET LEUR APPLICATION EN TANT QUE MEDICAMENTS

(84)	Designated Contracting States:
	AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR

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Priority:

27.12.2002 GB 0230217

(43)	Date of publication of application:
	21.09.2005 Bulletin 2005/38

(60)	Divisional application:
	07106112.1
	07107182.3

(73)	Proprietors:
	Biotica Technology Limited Nr Saffron Walden, Essex CB10 1XL (GB) THE UNIVERSITY OF OVIEDO 33003 Oviedo (ES)

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Inventors:

SALAS, Jose A., c/o The University of Oviedo
33006 Oviedo (ES)
MENDEZ, Carmen, c/o The University of Oviedo
33006 Oviedo (ES)
OLANO, Carlos, c/o The University of Oviedo
33006 Oviedo (ES)
SANCHEZ, Cesar, c/o The University of Oviedo
33006 Oviedo (ES)
BRANA, Alfredo F., c/o The University of Oviedo
33006 Oviedo (ES)
WILKINSON, Barrie, c/o Biotica Technology Limited
Nr Saffron Walden, Essex CB10 1XL (GB)
MARTIN, Christine J., c/o Biotica Technology Ltd
Nr Saffron Walden, Essex CB10 1XL (GB)
MOSS, Steven, c/o Biotica Technology Limited
Nr Saffron Walden, Essex CB10 1XL (GB)
LEADLAY, Peter F.,Biotica Technology Limited
Nr Saffron Walden,Essex CB10 1XL (GB)
OLIYNYK, Marko, c/o University of Cambridge
Cambridge, Cambridgeshire CB2 1GA (GB)

(74)	Representative: Teuten, Andrew John et al
	Sagittarius Intellectual Property Consultants Ltd Taylor House 39 High Street Marlow, Bucks. SL7 1AF Marlow, Bucks. SL7 1AF (GB)

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References cited: :

WO-A-01/09113

DE-A- 3 607 287

PATENT ABSTRACTS OF JAPAN vol. 1998, no. 01, 30 January 1998 (1998-01-30) & JP 09 227549 A (MERCIAN CORP; EISAI CO LTD), 2 September 1997 (1997-09-02)
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 11, 29 November 1996 (1996-11-29) & JP 08 173176 A (MERCIAN CORP; EISAI CO LTD), 9 July 1996 (1996-07-09)
DUFFEY MATTHEW O ET AL: "Enantioselective total synthesis of borrelidin." JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 12 FEB 2003, vol. 125, no. 6, 12 February 2003 (2003-02-12), pages 1458-1459, XP002362293 ISSN: 0002-7863
HADDAD N ET AL: "Studies Towards Total Synthesis of Borrelidin, Regioselective Methylation of Bis-epoxides and Structure Determination" TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 38, no. 34, August 1997 (1997-08), pages 6079-6082, XP004094193 ISSN: 0040-4039
HADDAD N ET AL: "Studies Towards Total Synthesis of Borrelidin, Stereoselective Synthesis of the Polysubstituted Macrolidic Part" TETRAHEDRON LETTERS, ELSEVIER, AMSTERDAM, NL, vol. 38, no. 34, August 1997 (1997-08), pages 6075-6078, XP004094192 ISSN: 0040-4039

Note: Within nine months from the publication of the mention of the grant of the European patent, any person may give notice to the European Patent Office of opposition to the European patent granted. Notice of opposition shall be filed in a written reasoned statement. It shall not be deemed to have been filed until the opposition fee has been paid. (Art. 99(1) European Patent Convention).