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(11)

EP 1 578 449 A2

(12)

(88) Date of publication A3: 26.08.2004 (43) Date of publication: 28.09.2005 Bulletin 2005/39 (21) Application number: 03813971.3 (22) Date of filing: 31.12.2003

(51) International Patent Classification (IPC)7: A61K 47/18, A61K 47/40, A61K 9/19 (86) International application number: PCT/IN2003/000423 (87) International publication number: WO 2004/058303 (15.07.2004 Gazette 2004/29)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 31.12.2002 IN MU11692002 (71) Applicant: Wockhardt Limited Mumbai 400 051 (IN)

(72) Inventors: SAOJI, Dilip G.Wockhardt Research Centre 431 210, Maharashtra (IN) NAGORI, Rajendra N.Wockhardt Research Centre 431 210, Maharashtra (IN) SHETTY, NitinWockhardt Research Centre 431 210, Maharashtra (IN) SHUKLA, Milind C.Wockhardt Research Centre 431 210, Maharashtra (IN) DE SOUZA, Noel J.Wockhardt Research Centre 431 210 Maharashtra (IN) (74) Representative: Ebner von Eschenbach, Jennifer et al LADAS & PARRY LLP Dachauerstrasse 37 80335 München 80335 München (DE)