(19)

(11)

EP 1 581 191 A1

(12)

(43) Date of publication: 05.10.2005 Bulletin 2005/40 (21) Application number: 03811976.4 (22) Date of filing: 25.11.2003

(51) International Patent Classification (IPC)7: A61K 9/16, A61K 9/20, A61K 31/43, A61K 31/424 (86) International application number: PCT/SI2003/000043 (87) International publication number: WO 2004/047808 (10.06.2004 Gazette 2004/24)

(84) Designated Contracting States: AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR Designated Extension States: AL LT LV MK (30) Priority: 26.11.2002 SI 200200282 24.09.2003 SI 200300247 (71) Applicant: LEK Pharmaceuticals d.d. 1526 Ljubljana (SI)	(72) Inventors: KERC, Janez 1000 Ljubljana (SI) SALOBIR, Mateja 1000 Ljubljana (SI) (74) Representative: Dietz, Jörg-Reimar et al Novartis AG Geistiges Eigentum Konzern Patent- und Markenabteilung CH Postfach 4002 Basel 4002 Basel (CH)