(19)
(11) EP 1 581 496 A2

(12)

(88) Date of publication A3:
23.09.2004

(43) Date of publication:
05.10.2005 Bulletin 2005/40

(21) Application number: 03812482.2

(22) Date of filing: 02.12.2003
(51) International Patent Classification (IPC)7C07D 211/60, C07D 211/08, C07D 401/00, A61K 31/445
(86) International application number:
PCT/US2003/038233
(87) International publication number:
WO 2004/050613 (17.06.2004 Gazette 2004/25)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 02.12.2002 US 430556 P

(71) Applicant: GILEAD SCIENCES, INC.
California 94404 (US)

(72) Inventors:
  • SZNAIDMAN, Marcos
    Durham, NC 27713 (US)
  • PAINTER, George, R.
    Chapel Hill, NC 27514 (US)
  • ALMOND, Merrick, R.
    Apex, NC 27502 (US)
  • CLEARY, Darryl, G.
    Chapel Hill, NC 27514 (US)
  • PESYAN, Amir
    Park City, UT 84098 (US)

(74) Representative: Hallybone, Huw George et al
Carpmaels and Ransford, 43 Bloomsbury Square
London WC1A 2RA
London WC1A 2RA (GB)

   


(54) 2-SUBSTITUTED-3-PROPENAMIDE DERIVATIVES AND METHODS OF USING THE SAME