(19)
(11) EP 1 581 507 A1

(12)

(43) Date of publication:
05.10.2005 Bulletin 2005/40

(21) Application number: 03780483.8

(22) Date of filing: 30.12.2003
(51) International Patent Classification (IPC)7C07D 249/12, C07D 233/70, A61K 31/4196, A61P 11/00, A61P 37/00
(86) International application number:
PCT/IB2003/006232
(87) International publication number:
WO 2004/058731 (15.07.2004 Gazette 2004/29)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 31.12.2002 US 437228 P

(71) Applicant: Pfizer Products Inc.
Connecticut 06340 (US)

(72) Inventors:
  • DUPLANTIER, Allen J.,c/o Pfizer Global R & D
    Groton, CT 06340 (US)
  • SUBRAMANYAM, Chakrapani,c/o Pfizer Global R & D
    Groton, CT 06340 (US)
  • DOMBROSKI, Mark A.,c/o Pfizer Global R & D
    Groton, CT 06340 (US)

(74) Representative: Swarbrick, Terry Mark et al
Pfizer Limited European Pharmaceutical Patent Department Ramsgate Road
Sandwich, Kent CT13 9NJ
Sandwich, Kent CT13 9NJ (GB)

   


(54) BENZAMIDE INHIBITORS OF THE P2X7 RECEPTOR