(19)
(11) EP 1 581 795 A2

(12)

(43) Date of publication:
05.10.2005 Bulletin 2005/40

(21) Application number: 03799777.2

(22) Date of filing: 09.05.2003
(51) International Patent Classification (IPC)7: G01N 1/00
(86) International application number:
PCT/US2003/014736
(87) International publication number:
WO 2004/042348 (21.05.2004 Gazette 2004/21)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 16.05.2002 US 381159 P
17.05.2002 US 381223 P
17.05.2002 US 381151 P
17.05.2002 US 381177 P

(71) Applicant: Icoria, Inc.
Research Triangle Park, NC 27709-4528 (US)

(72) Inventors:
  • TANZER, Matthew
    Durham, NC 27707 (US)
  • MAHANTY, Sanjoy
    Chapel Hill, NC 27516 (US)
  • DARVEAUX, Blaise
    Hillsborough, NC 27278 (US)
  • HEINIGER, Ryan
    Raleigh, NC 27603 (US)
  • AKALCHUNES, Amy
    Raleigh, NC 27609 (US)
  • PAN, Huaqin
    Apex, NC 27502 (US)
  • TARPEY, Rex
    Apex, NC 27502 (US)
  • SHUSTER, Jeffrey
    Chapel Hill, NC 27516 (US)
  • HAMER, Lisbeth
    Durham, NC 27707 (US)
  • ADACHI, Kiichi
    Nerima,Tokyo 177-0034 (JP)
  • DEZWAAN, Todd
    Apex, NC 27502 (US)
  • LO, Sze Chung
    Shun Lee Estate,Hong Kong (CN)
  • MONTENEGRO-CHAMORRO, Maria Victoria
    Morrisville, NC 27560 (US)
  • FRANK, Sheryl
    Durham, NC 27713 (US)

(74) Representative: Kensett, John Hinton 
Saunders & Dolleymore, 9 Rickmansworth Road Watford,
Hertfordshire WD18 0JU
Hertfordshire WD18 0JU (GB)

   


(54) METHODS FOR THE IDENTIFICATION OF INHIBITORS OF CHITIN SYNTHASE 2, S-ADENOSYLMETHIONINE DECARBOXYLASE, PUTRESCINE AMINOPROPYLTRANSFERASE, AND METHYLENETE TRAHYDROFOLATE REDUCTASE AS ANTIBIOTICS