(19)
(11) EP 1 583 747 A2

(12)

(88) Date of publication A3:
27.01.2005

(43) Date of publication:
12.10.2005 Bulletin 2005/41

(21) Application number: 03800372.9

(22) Date of filing: 31.12.2003
(51) International Patent Classification (IPC)7C07D 239/00
(86) International application number:
PCT/US2003/041661
(87) International publication number:
WO 2004/060878 (22.07.2004 Gazette 2004/30)
(84) Designated Contracting States:
AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HU IE IT LI LU MC NL PT RO SE SI SK TR
Designated Extension States:
AL LT LV MK

(30) Priority: 31.12.2002 US 437576 P

(71) Applicant: VERTEX PHARMACEUTICALS INCORPORATED
Cambridge, MA 02139 (US)

(72) Inventors:
  • SAUNDERS, Jeffrey, O.
    Acton, MA 01720 (US)
  • MIKNIS, Gregory, F.
    Broomfield, CO 80020 (US)
  • BUCKMELTER, Alexandre, J.
    Superior, CO 80027 (US)
  • HUNT, Kevin, W.
    Longmont, CO 80501 (US)
  • BLAKE, James, F.
    Longmont, CO 80504 (US)
  • VIGERS, Guy, P., A.
    Boulder, CO 80304 (US)
  • SUN, Xicheng
    Superior, CO 80027 (US)

(74) Representative: Cornish, Kristina Victoria Joy et al
Kilburn & Strode, 20 Red Lion Street
London WC1R 4PJ
London WC1R 4PJ (GB)

   


(54) INHIBITORS OF PHOSPHATASES